MCEE Protein (AA 37-176) (His tag)

Produktnummer ABIN7505580

Produktdetails

Target: MCEE (Methylmalonyl CoA Epimerase (MCEE))

Protein-Typ: Recombinant

Proteineigenschaft: AA 37-176

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses MCEE Protein ist gelabelt mit His tag.

Sequenz: Gln37-Ala176

Produktmerkmale: Recombinant Human Methylmalonyl-CoA epimerase is produced by our Mammalian expression system and the target gene encoding Gln37-Ala176 is expressed with a 6His tag at the C-terminus.

Reinheit: >95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: <1.0 EU per μg of the protein as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: MCEE (Methylmalonyl CoA Epimerase (MCEE))

Andere Bezeichnung: MCEE (MCEE Produkte)

Synonyme: MGC89112 Protein, zgc:112343 Protein, MGC116480 Protein, GLOD2 Protein, 1110007A04Rik Protein, methylmalonyl-CoA epimerase Protein, methylmalonyl CoA epimerase Protein, methylmalonyl-CoA epimerase S homeolog Protein, MCEE Protein, mcee Protein, mcee.S Protein, Mcee Protein

Hintergrund:

Background: Methylmalonyl-CoA epimerase, mitochondrial(MCEE)is an enzyme which belongs to the glyoxalase I family. It converts (S)-methylmalonyl-CoA to the (R) form, catalyses the following chemical reaction: (R)-methylmalonyl-CoA (S)-methylmalonyl-CoA. It plays an important role in the catabolism of fatty acids with odd-length carbon chains. This protein deficiency is an autosomal recessive inborn error of AA metabolism, involving valine, threonine, isoleucine and methionine. This organic aciduria can appear in the neonatal period with life-threatening metabolic acidosis, hyperammonemia, feeding difficulties, pancytopenia and coma.

Synonym: Methylmalonyl-CoA epimerase, mitochondrial,DL-methylmalonyl-CoA racemase

Molekulargewicht: 16.0 kDa

UniProt: Q96PE7

Pathways: Monocarboxylic Acid Catabolic Process