NT-ProBNP Protein (AA 27-76) (GST tag)

Produktnummer ABIN7505496

Produktdetails

Target: NT-ProBNP (Pro-Brain Natriuretic Peptide (NT-ProBNP) (NT-ProBNP))

Protein-Typ: Recombinant

Proteineigenschaft: AA 27-76

Spezies: Ratte

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses NT-ProBNP Protein ist gelabelt mit GST tag.

Sequenz: His27-Arg76

Produktmerkmale: A DNA sequence encoding the Rat NT-proBNP protein (P13205) (His27-Arg76) was expressed with a GST.

Reinheit: >95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: NT-ProBNP (Pro-Brain Natriuretic Peptide (NT-ProBNP) (NT-ProBNP))

Andere Bezeichnung: NT-proBNP (NT-ProBNP Produkte)

Hintergrund:

Background: NT-proBNP, or Brain Natriuretic Peptide, is a hormone expressed by cardiomyocytes by the gene NPPB. NT-proBNP is synthesized as a 134- amino acid preprohormone (prepro-BNP), subsequent removal of a 25 amino acid signal peptide forms pro-BNP, which is stored intracellularly. Pro-BNP is secreted as an inactive prohormone and cleavage by furin or corin forms NT-pro-BNP and the active 32- amino acid BNP-32 peptide. BNP may function as a paracrine antifibrotic factor in the heart, as well as have a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion.

Synonym: Natriuretic peptides B, ANFB_RAT, Nppb,Brain natriuretic factor prohormone, preproBNP, proBNP,Gamma-brain natriuretic peptide, Iso-ANP,

Molekulargewicht: 30.39 kDa

UniProt: P13205