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Uromodulin Protein (UMOD) (AA 25-587) (His tag)

UMOD Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >85 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7505005
  • Target Alle Uromodulin (UMOD) Proteine anzeigen
    Uromodulin (UMOD)
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 25-587
    Spezies
    • 7
    • 3
    • 3
    • 3
    • 1
    • 1
    Human
    Quelle
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses Uromodulin Protein ist gelabelt mit His tag.
    Sequenz
    Asp25-Phe587
    Produktmerkmale
    A DNA sequence encoding theHuman THP protein (P07911) (Asp25-Phe587) was expressed with a N-His.
    Reinheit
    >85 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product UMOD Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Haltbarkeit
    12 months
  • Target
    Uromodulin (UMOD)
    Andere Bezeichnung
    THP (UMOD Produkte)
    Synonyme
    ADMCKD2 Protein, FJHN Protein, HNFJ Protein, HNFJ1 Protein, MCKD2 Protein, THGP Protein, THP Protein, urehr4 Protein, uromodulin Protein, UMOD Protein, Umod Protein
    Hintergrund

    Background: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability (Probable). May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF.Facilitates neutrophil migration across renal epithelia.

    Synonym: Tamm-Horsfall urinary glycoprotein

    Molekulargewicht
    61.4 kDa
    UniProt
    P07911
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