SETD7 Protein (AA 1-366) (His tag)

Produktnummer ABIN7504524

Produktdetails

Target: SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-366

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses SETD7 Protein ist gelabelt mit His tag.

Verwendungszweck: Human SETD7 Protein

Sequenz: Met1-Lys366

Produktmerkmale: Recombinant Human SETD7 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Met1-Lys366.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))

Andere Bezeichnung: SETD7 (SETD7 Produkte)

Synonyme: KMT7 Protein, SET7 Protein, SET7/9 Protein, SET9 Protein, set7 Protein, zgc:101860 Protein, zgc:92330 Protein, 1600028F23Rik Protein, H3K4MT Protein, Set7 Protein, Set7/9 Protein, mKIAA1717 Protein, SET domain containing lysine methyltransferase 7 Protein, SET domain containing (lysine methyltransferase) 7 Protein, SETD7 Protein, setd7 Protein, Setd7 Protein

Hintergrund: SETD7 is a methyltransferase that specifically catalyzes the monomethylation of lysine 4 on histone H3. A variety of studies has revealed the role of SETD7 in posttranslational modifications of non-histone proteins. Aberrant expression of SETD7 has been associated with various diseases, including cancer. As a prognostic marker of breast cancer and a novel antioxidant promoter under oxidative stress in breast cancer, SETD7 is considered a good target for the development of new epigenetic drugs.

Molekulargewicht: 41.68 kDa. The protein migrates to 47-50 kDa based on Tris-Bis PAGE result.

NCBI Accession: NP_085151