RSV Fusion Protein Protein (His tag)

Produktnummer ABIN7504521

Produktdetails

Target: RSV Fusion Protein (RSV F) (Respiratory Syncytial Virus Fusion Protein (RSV F))

Protein-Typ: Recombinant

Spezies: Respiratory Syncytial Virus (RSV)

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses RSV Fusion Protein Protein ist gelabelt mit His tag.

Verwendungszweck: RSV (A) Pre-fusion glycoprotein F0 Protein

Produktmerkmale: Recombinant RSV (A) Pre-fusion glycoprotein F0 Protein is expressed from HEK293 with His tag at the C-terminus.

Reinheit: > 95 % as determined by Tris-Bis PAGE

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: RSV Fusion Protein (RSV F) (Respiratory Syncytial Virus Fusion Protein (RSV F))

Andere Bezeichnung: RSV Pre-fusion glycoprotein F0 (RSV F Produkte)

Hintergrund: Respiratory syncytial virus (RSV) is a highly contagious childhood pathogen of the respiratory tract and is divided into two antigenic subtypes, A and B, based on the reactivity of the F and G surface proteins to monoclonal antibodies. Surface protein F (fusion protein) is responsible for fusion of viral and host cell membranes, as well as syncytium formation between viral particles. Its sequence is highly conserved between strains. F protein exists in multiple conformational forms. In the prefusion state (PreF), the protein exists in a trimeric form and contains the major antigenic site which serves as a primary target of neutralizing antibodies in the body.

Molekulargewicht: 56.28 kDa. Due to glycosylation, the protein migrates to 57-70 kDa based on Tris-Bis PAGE result.