LY6G6D Protein (AA 20-104) (His tag)

Produktnummer ABIN7504461

Produktdetails

Target: LY6G6D (Lymphocyte Antigen 6 Complex, Locus G6D (LY6G6D))

Protein-Typ: Recombinant

Proteineigenschaft: AA 20-104

Spezies: Cynomolgus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses LY6G6D Protein ist gelabelt mit His tag.

Verwendungszweck: Cynomolgus LY6G6D Protein

Sequenz: Asn20-Ser104

Produktmerkmale: Recombinant Cynomolgus LY6G6D Protein is expressed from HEK293 with His tag at the N-terminus.It contains Asn20-Ser104.

Reinheit: > 95 % as determined by Tris-Bis PAGE

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: LY6G6D (Lymphocyte Antigen 6 Complex, Locus G6D (LY6G6D))

Andere Bezeichnung: LY6G6D (LY6G6D Produkte)

Synonyme: C6orf23 Protein, G6D Protein, LY6-D Protein, MEGT1 Protein, NG25 Protein, A930024F17Rik Protein, G6d Protein, G6f Protein, NG32 Protein, Ly6-D Protein, Ng25 Protein, lymphocyte antigen 6 family member G6D Protein, lymphocyte antigen 6 complex, locus G6D Protein, LY6G6D Protein, Ly6g6d Protein

Hintergrund: LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utilized to potently re-direct and activate cytotoxic T-cells to lyse LY6G6D expressing CRC using a TcE. This effect can be spread to target negative neighboring tumor cells, potentially leading to improved therapeutic efficacy.

Molekulargewicht: 10.22 kDa. Due to glycosylation, the protein migrates to 14-24 kDa based on Tris-Bis PAGE result.

NCBI Accession: XP_045246087