CEACAM7 Protein (AA 36-242) (His tag)

Produktnummer ABIN7504297

Produktdetails

Target: CEACAM7 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7 (CEACAM7))

Protein-Typ: Recombinant

Proteineigenschaft: AA 36-242

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CEACAM7 Protein ist gelabelt mit His tag.

Verwendungszweck: Human CEACAM-7 Protein

Sequenz: Thr36-Ser242

Produktmerkmale: Recombinant Human CEACAM-7 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Thr36-Ser242.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: CEACAM7 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 7 (CEACAM7))

Andere Bezeichnung: CEACAM-7 (CEACAM7 Produkte)

Synonyme: CEACAM7 Protein, CEA Protein, CGM2 Protein, carcinoembryonic antigen related cell adhesion molecule 7 Protein, carcinoembryonic antigen-related cell adhesion molecule 6 Protein, CEACAM7 Protein, LOC612471 Protein

Hintergrund: Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin-related glycoproteins. They are involved in cell-cell recognition and modulate cellular processes that range from the shaping of tissue architecture and neovascularization to the regulation of insulin homeostasis and T-cell proliferation. CEACAM7 (CGM2), a member of the CEA family of proteins with expression restricted to the colon and pancreas, as a potential CAR T-cell target for PDAC.

Molekulargewicht: 24.45 kDa. Due to glycosylation, the protein migrates to 45-65 kDa based on Tris-Bis PAGE result.