BTN2A1 Protein (AA 29-248) (His tag,DYKDDDDK Tag)

Produktnummer ABIN7504248

Produktdetails

Target: BTN2A1 (butyrophilin, Subfamily 2, Member A1 (BTN2A1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 29-248

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses BTN2A1 Protein ist gelabelt mit His tag,DYKDDDDK Tag.

Verwendungszweck: Human BTN2A1 & BTN3A1 complex Protein

Sequenz: Gln29-Ala248 (BTN2A1) acidic tail & Gln30-Gly254 (BTN3A1) basic tail

Spezifität: Uni-Prot: Q7KYR7-1 (BTN2A1), O00481-1 (BTN3A1)

Produktmerkmale: Recombinant Human BTN2A1 & BTN3A1 complex Protein is expressed from HEK293 with His tag and Flag tag at the C-terminus.It contains Gln29-Ala248 (BTN2A1) acidic tail and Gln30-Gly254 (BTN3A1) basic tail.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: BTN2A1 (butyrophilin, Subfamily 2, Member A1 (BTN2A1))

Andere Bezeichnung: BTN2A1 (BTN2A1 Produkte)

Synonyme: BK14H9.1 Protein, BT2.1 Protein, BTF1 Protein, DJ3E1.1 Protein, BTN2A1 Protein, btf1 Protein, bt2.1 Protein, BTN2A2 Protein, butyrophilin subfamily 2 member A1 Protein, butyrophilin subfamily 2 member A1 S homeolog Protein, butyrophilin, subfamily 2, member A1 Protein, BTN2A1 Protein, btn2a1.S Protein, btn2a1 Protein, LOC100409586 Protein

Hintergrund: BTN2A1 and BTN3A1 clearly play highly distinct roles in Vγ9Vδ2 T cell detection of P-Ag-exposed cells. BTN2A1&BTN3A1, a protein complex which contains heterodimeric BTN2A1 and BTN3A1 extracellular domains (ECD), is critical to enhance cytotoxic killing by Vγ9Vδ2 T cells.

Molekulargewicht: 30.74 kDa (BTN2A1) and 30.25 kDa (BTN3A1). Due to glycosylation, the protein migrates to 53-63 kDa (BTN2A1) and 33-38 kDa (BTN3A1) based on Tris-Bis PAGE result.

Pathways: Activated T Cell Proliferation