LRP1 Protein (Fc Tag)

Produktnummer ABIN7482511

Produktdetails

Target: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses LRP1 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Human LRP-1 / cluster II Protein, Fc Tag (MALS verified)

Sequenz: Arg 786 - Leu 1165

Produktmerkmale: Human cluster II Protein, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Arg 786 - Leu 1165 (Accession # Q07954-1).

Reinheit: 95 %

Endotoxin-Niveau: 0.1 EU per μg

Güteklasse: MALS verified

Anwendungsinformationen

Kommentare:

This protein carries a human IgG1 Fc tag at the C-terminus. (Fc) The protein has a calculated MW of 68.0kDa. The protein migrates as 75-105 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Antigendetails

Target: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Andere Bezeichnung: LRP-1 (LRP1 Produkte)

Synonyme: A2MR Protein, APOER Protein, APR Protein, CD91 Protein, IGFBP3R Protein, LRP Protein, LRP1A Protein, TGFBR5 Protein, A2mr Protein, AI316852 Protein, Lrp Protein, LRP-1 Protein, LDL receptor related protein 1 Protein, prolow-density lipoprotein receptor-related protein 1 Protein, low density lipoprotein receptor-related protein 1 Protein, LRP1 Protein, Lrp1 Protein, LOC100414789 Protein

Hintergrund: Low density lipoprotein receptor-related protein 1 (LRP1), also known as alpha-2-macroglobulin receptor (A2MR), apolipoprotein E receptor (APOER) or cluster of differentiation 91 (CD91), is a protein forming a receptor found in the plasma membrane of cells. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor. LRP1 is also a key signalling protein and, thus, involved in various biological processes, such as lipoprotein metabolism and cell motility, and diseases, such as neurodegenerative diseases, atherosclerosis, and cancer.

Molekulargewicht: 68.0kDa

Pathways: Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling