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KIR3DL3 Protein (Biotin,Fc-Avi Tag)

KIR3DL3 Spezies: Human Wirt: HEK-293 Cells Recombinant 90 %
Produktnummer ABIN7489016
  • Target Alle KIR3DL3 Produkte
    KIR3DL3 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 3 (KIR3DL3))
    Protein-Typ
    Recombinant
    Spezies
    Human
    Quelle
    • 3
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses KIR3DL3 Protein ist gelabelt mit Biotin,Fc-Avi Tag.
    Verwendungszweck
    Biotinylated Human KIR3DL3 / CD158z Protein, Fc,Avitag™
    Sequenz
    Gln 26 - Leu 322
    Produktmerkmale
    Biotinylated Human KIR3DL3 / CD158z Protein, Fc,Avitag is expressed from human 293 cells (HEK293). It contains AA Gln 26 - Leu 322 (Accession # Q8N743-1).
    Reinheit
    90 %
    Endotoxin-Niveau
    1.0 EU per μg
  • Kommentare

    This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). (Biotin,Fc , Avi) The protein has a calculated MW of 60.4 kDa. The protein migrates as 66-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4, 25 mM Arginine
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C
  • Target
    KIR3DL3 (Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 3 (KIR3DL3))
    Andere Bezeichnung
    KIR3DL3 (KIR3DL3 Produkte)
    Synonyme
    CD158Z Protein, KIR3DL7 Protein, KIR44 Protein, KIRC1 Protein, killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3 Protein, KIR3DL3 Protein
    Hintergrund
    KIR3DL3 (Killer Cell Immunoglobulin Like Receptor) is the inhibitory KIR surface receptors possessing three extracellular immunoglobin (Ig) domains (3D) and only one inhibitory motif within the long cytoplasmic domain (L) due to a premature stop codon. Moreover, exon 6 of KIR3DL3 encoding the stem part of the receptor is also absent, which differs from other inhibitory KIRs. Understanding the function of KIR3DL3 is further complicated by the unknown identity of the specific ligand, but its importance is highlighted by its presence in all human KIR haplotypes with 120 distinct polymorphic alleles of the coding sequence.
    Molekulargewicht
    60.4 kDa
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