Apelin Receptor Protein (APLNR)

Produktnummer ABIN7491545

Produktdetails

Target: Apelin Receptor (APLNR)

Protein-Typ: Synthetic

Spezies: Human

Quelle: HEK-293 Cells

Verwendungszweck: Human APLNR full length protein-synthetic nanodisc

Produktmerkmale: Full Length Transmembrane Proteins (synthetic Nanodisc)

Anwendungsinformationen

Applikationshinweise:

• Applications for VLPs:
• ELISA
• SPR affinity analysis
• Phage display screening
• Immunization
• Cell based assays
• CAR-T cell screening
• Protein cystal structure analysis

Kommentare:

Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: Apelin Receptor (APLNR)

Andere Bezeichnung: APLNR (APLNR Produkte)

Synonyme: AGTRL1 Protein, APJ Protein, APJR Protein, HG11 Protein, Agtrl1 Protein, msr/apj Protein, Apj Protein, X-msr Protein, Xangio1 Protein, Xmsr Protein, agtrl1 Protein, angio1 Protein, apj Protein, apjr Protein, hg11 Protein, msr Protein, APLNR Protein, DKFZp469C1532 Protein, agtrl1-B Protein, agtrl1b Protein, Agtrl1a Protein, grn Protein, zgc:114063 Protein, APJa Protein, XAngio1 Protein, agtrl1-A Protein, agtrl1a Protein, aplnr-a Protein, aplnr-b Protein, x-MSR Protein, xAngio1 Protein, APLNR1 Protein, apelin receptor Protein, apelin receptor S homeolog Protein, apelin receptor b Protein, apelin receptor L homeolog Protein, APLNR Protein, Aplnr Protein, aplnr Protein, aplnr.S Protein, aplnrb Protein, aplnr.L Protein

Hintergrund: AGTRL1, APJ, APJR, HG11
Description: This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq, Jul 2009]

Molekulargewicht: The human full length APLNR protein has a MW of 42.7 kDa

UniProt: P35414