GPR65 Protein

Produktnummer ABIN7491665

Produktdetails

Target: GPR65 (G Protein-Coupled Receptor 65 (GPR65))

Protein-Typ: Synthetic

Spezies: Human

Quelle: HEK-293 Cells

Verwendungszweck: Human GPR65 full length protein-synthetic nanodisc

Produktmerkmale: Full Length Transmembrane Proteins (synthetic Nanodisc)

Anwendungsinformationen

Applikationshinweise:

• Applications for VLPs:
• ELISA
• SPR affinity analysis
• Phage display screening
• Immunization
• Cell based assays
• CAR-T cell screening
• Protein cystal structure analysis

Kommentare:

Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: GPR65 (G Protein-Coupled Receptor 65 (GPR65))

Andere Bezeichnung: GPR65 (GPR65 Produkte)

Synonyme: tdag8 Protein, htdag8 Protein, TDAG8 Protein, hTDAG8 Protein, Dig1 Protein, Gpcr25 Protein, Tdag8 Protein, G protein-coupled receptor 65 Protein, G-protein coupled receptor 65 Protein, GPR65 Protein, gpr65 Protein, Gpr65 Protein

Hintergrund: HTDAG8, TDAG8
Description: Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids (PubMed:11309421). Plays a role in immune response by maintaining lysosome function and supporting phagocytosis-mediated intracellular bacteria clearance (PubMed:27287411). May have a role in activation-induced cell death or differentiation of T-cells (By similarity).[UniProtKB/Swiss-Prot Function]

Molekulargewicht: The human full length GPR65 protein has a MW of 39.3 kDa

UniProt: Q8IYL9

Pathways: cAMP Metabolic Process