CXCR7 Protein

Produktnummer ABIN7491631

Produktdetails

Target: CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

Protein-Typ: Synthetic

Spezies: Human

Quelle: HEK-293 Cells

Verwendungszweck: Human ACKR3 full length protein-synthetic nanodisc

Produktmerkmale: Full Length Transmembrane Proteins (synthetic Nanodisc)

Anwendungsinformationen

Applikationshinweise:

• Applications for VLPs:
• ELISA
• SPR affinity analysis
• Phage display screening
• Immunization
• Cell based assays
• CAR-T cell screening
• Protein cystal structure analysis

Kommentare:

Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

Andere Bezeichnung: ACKR3 (CXCR7 Produkte)

Synonyme: CMKOR1 Protein, CXC-R7 Protein, CXCR-7 Protein, CXCR7 Protein, GPR159 Protein, RDC-1 Protein, RDC1 Protein, AW541270 Protein, Cmkor1 Protein, Cxcr7 Protein, Rdc1 Protein, ackr3 Protein, cxcr7 Protein, rdc1 Protein, xcxcr7 Protein, atypical chemokine receptor 3 Protein, ORF 74; similar to Kaposi's sarcoma-associated herpesvirus ORF 74 Protein, atypical chemokine receptor 3 L homeolog Protein, ACKR3 Protein, MmrVgp88 Protein, Ackr3 Protein, ackr3.L Protein

Hintergrund: CMKOR1, CXC-R7, CXCR-7, CXCR7, GPR159, RDC-1, RDC1
Description: This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq, Jul 2008]

Molekulargewicht: The human full length ACKR3 protein has a MW of 41.3 kDa

UniProt: P25106

Pathways: Myometrial Relaxation and Contraction, Negative Regulation of intrinsic apoptotic Signaling