ADGRE2 Protein
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- Target Alle ADGRE2 Produkte
- ADGRE2 (Adhesion G protein-coupled Receptor E2 (ADGRE2))
- Protein-Typ
- Synthetic
- Spezies
- Human
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Quelle
- HEK-293 Cells
- Verwendungszweck
- Human ADGRE2 full length protein-synthetic nanodisc
- Produktmerkmale
- Full Length Transmembrane Proteins (synthetic Nanodisc)
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Adhesion G protein-coupled Receptor E2 (ADGRE2) (AA 24-540) protein (His tag)
Crystallography grade ADGRE2 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
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- Applikationshinweise
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Kommentare
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Haltbarkeit
- 12 months
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- Target
- ADGRE2 (Adhesion G protein-coupled Receptor E2 (ADGRE2))
- Andere Bezeichnung
- ADGRE2 (ADGRE2 Produkte)
- Synonyme
- CD312 Protein, adhesion G protein-coupled receptor E2 Protein, ADGRE2 Protein
- Hintergrund
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CD312, CD97, EMR2, VBU
Description: This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012] - Molekulargewicht
- The human full length ADGRE2 protein has a MW of 90.5 kDa
- UniProt
- Q9UHX3
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