Claudin 7 Protein (CLDN7)
-
- Target Alle Claudin 7 (CLDN7) Proteine anzeigen
- Claudin 7 (CLDN7)
- Protein-Typ
- Synthetic
-
Spezies
- Human
-
Quelle
- HEK-293 Cells
- Verwendungszweck
- Human CLDN7 full length protein-synthetic nanodisc
- Produktmerkmale
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product CLDN7 Protein
-
-
- Applikationshinweise
-
- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Kommentare
-
Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Haltbarkeit
- 12 months
-
- Target
- Claudin 7 (CLDN7)
- Andere Bezeichnung
- CLDN7 (CLDN7 Produkte)
- Synonyme
- cb388 Protein, claudin7 Protein, cldn7 Protein, wu:fd19f08 Protein, MGC53400 Protein, MGC75689 Protein, CLDN7 Protein, CEPTRL2 Protein, CLDN-7 Protein, CPETRL2 Protein, Hs.84359 Protein, claudin-1 Protein, claudin 7b Protein, claudin 7 L homeolog Protein, claudin 7 Protein, cldn7b Protein, cldn7.L Protein, cldn7 Protein, CLDN7 Protein, Cldn7 Protein
- Hintergrund
-
CEPTRL2, claudin-1, CLDN-7, CPETRL2, Hs.84359
Description: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, May 2010] - Molekulargewicht
- The human full length CLDN7 protein has a MW of 22.9 kDa
- UniProt
- O95471
- Pathways
- Hepatitis C
-