ESYT1 Protein

Produktnummer ABIN7491635

Produktdetails

Target: ESYT1 (Extended Synaptotagmin-Like Protein 1 (ESYT1))

Protein-Typ: Synthetic

Spezies: Human

Quelle: HEK-293 Cells

Verwendungszweck: Human ESYT1 full length protein-synthetic nanodisc

Produktmerkmale: Full Length Transmembrane Proteins (synthetic Nanodisc)

Anwendungsinformationen

Applikationshinweise:

• Applications for VLPs:
• ELISA
• SPR affinity analysis
• Phage display screening
• Immunization
• Cell based assays
• CAR-T cell screening
• Protein cystal structure analysis

Kommentare:

Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: ESYT1 (Extended Synaptotagmin-Like Protein 1 (ESYT1))

Andere Bezeichnung: ESYT1 (ESYT1 Produkte)

Synonyme: FAM62A Protein, fam62a Protein, si:ch211-239j9.4 Protein, DKFZp459I1628 Protein, MBC2 Protein, Fam62a Protein, Mbc2 Protein, vp115 Protein, extended synaptotagmin 1 Protein, extended synaptotagmin-like protein 1b Protein, extended synaptotagmin-like protein 1 Protein, ESYT1 Protein, esyt1b Protein, Esyt1 Protein

Hintergrund: FAM62A, MBC2
Description: Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity). Binds calcium (via the C2 domains) and translocates to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels. Helps tether the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane.[UniProtKB/Swiss-Prot Function]

Molekulargewicht: The human full length ESYT1 protein has a MW of 122.9 kDa

UniProt: Q9BSJ8