KCNK9 Protein

Produktnummer ABIN7491685

Produktdetails

Target: KCNK9 (Potassium Channel, Subfamily K, Member 9 (KCNK9))

Protein-Typ: Synthetic

Spezies: Human

Quelle: HEK-293 Cells

Verwendungszweck: Human KCNK9 full length protein-synthetic nanodisc

Produktmerkmale: Full Length Transmembrane Proteins (synthetic Nanodisc)

Anwendungsinformationen

Applikationshinweise:

• Applications for VLPs:
• ELISA
• SPR affinity analysis
• Phage display screening
• Immunization
• Cell based assays
• CAR-T cell screening
• Protein cystal structure analysis

Kommentare:

Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: KCNK9 (Potassium Channel, Subfamily K, Member 9 (KCNK9))

Andere Bezeichnung: KCNK9 (KCNK9 Produkte)

Synonyme: Task3 Protein, K2p9.1 Protein, KT3.2 Protein, TASK-3 Protein, TASK3 Protein, KCNK9 Protein, LOC799704 Protein, Kcnk9 Protein, task3 Protein, k2p9.1 Protein, task-3 Protein, kt3.2 Protein, potassium channel, subfamily K, member 9 Protein, potassium two pore domain channel subfamily K member 9 Protein, potassium channel, two pore domain subfamily K, member 9 Protein, potassium channel, two pore domain subfamily K, member 9 L homeolog Protein, Kcnk9 Protein, KCNK9 Protein, kcnk9 Protein, kcnk9.L Protein

Hintergrund: This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH -dependent potassium channel. Amplification and overexpression of this gene have been observed in several types of human carcinomas. This gene is imprinted in the brain, with preferential expression from the maternal allele. A mutation in this gene was associated with Birk-Barel dysmorphism syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]

Molekulargewicht: The human full length KCNK9 protein has a MW of 42.3 kDa

UniProt: Q9NPC2