CD133 Protein

Produktnummer ABIN7491715

Produktdetails

Target: CD133 (PROM1) (Prominin 1 (PROM1))

Protein-Typ: Synthetic

Spezies: Human

Quelle: HEK-293 Cells

Verwendungszweck: Human PROM1 full length protein-synthetic nanodisc

Produktmerkmale: Full Length Transmembrane Proteins (synthetic Nanodisc)

Anwendungsinformationen

Applikationshinweise:

• Applications for VLPs:
• ELISA
• SPR affinity analysis
• Phage display screening
• Immunization
• Cell based assays
• CAR-T cell screening
• Protein cystal structure analysis

Kommentare:

Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: CD133 (PROM1) (Prominin 1 (PROM1))

Andere Bezeichnung: PROM1 (PROM1 Produkte)

Synonyme: Prom Protein, AC133 Protein, CD133 Protein, Prom-1 Protein, Proml1 Protein, 4932416E19Rik Protein, CORD12 Protein, MCDR2 Protein, PROML1 Protein, RP41 Protein, STGD4 Protein, prominin 1 Protein, Prom1 Protein, PROM1 Protein

Hintergrund: AC133, CD133, CORD12, MCDR2, MSTP061, PROML1, RP41, STGD4
Description: This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Molekulargewicht: The human full length PROM1 protein has a MW of 97 kDa

UniProt: O43490