STEAP2 Protein

Produktnummer ABIN7491745

Produktdetails

Target: STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

Protein-Typ: Synthetic

Spezies: Human

Quelle: HEK-293 Cells

Verwendungszweck: Human STEAP2 full length protein-synthetic nanodisc

Produktmerkmale: Full Length Transmembrane Proteins (synthetic Nanodisc)

Anwendungsinformationen

Applikationshinweise:

• Applications for VLPs:
• ELISA
• SPR affinity analysis
• Phage display screening
• Immunization
• Cell based assays
• CAR-T cell screening
• Protein cystal structure analysis

Kommentare:

Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

Andere Bezeichnung: STEAP2 (STEAP2 Produkte)

Synonyme: 4921538B17Rik Protein, AI930049 Protein, AW045895 Protein, IPCA-1 Protein, IPCA1 Protein, PCANAP1 Protein, STAMP1 Protein, STMP Protein, PUMPCn Protein, six transmembrane epithelial antigen of prostate 2 Protein, STEAP2 metalloreductase Protein, Steap2 Protein, STEAP2 Protein

Hintergrund: IPCA1, PCANAP1, PUMPCn, STAMP1, STMP
Description: This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Molekulargewicht: The human full length STEAP2 protein has a MW of 55.9 kDa

UniProt: Q8NFT2

Pathways: Transition Metal Ion Homeostasis