TRPA1 Protein

Produktnummer ABIN7491751

Produktdetails

Target: TRPA1 (Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1))

Protein-Typ: Synthetic

Spezies: Human

Quelle: HEK-293 Cells

Verwendungszweck: Human TRPA1 full length protein-synthetic nanodisc

Produktmerkmale: Full Length Transmembrane Proteins (synthetic Nanodisc)

Anwendungsinformationen

Applikationshinweise:

• Applications for VLPs:
• ELISA
• SPR affinity analysis
• Phage display screening
• Immunization
• Cell based assays
• CAR-T cell screening
• Protein cystal structure analysis

Kommentare:

Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: TRPA1 (Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1))

Andere Bezeichnung: TRPA1 (TRPA1 Produkte)

Synonyme: trpa1 Protein, ANKTM1 Protein, Anktm1 Protein, CG5751 Protein, CG5761 Protein, CT18073 Protein, DmTRPA1 Protein, Dmel\\CG5751 Protein, TRPA Protein, TRPA1 Protein, TrpA Protein, dANKTM1 Protein, dTRPA Protein, dTRPA1 Protein, dTrpA Protein, dTrpA1 Protein, dtrpA1 Protein, trpA1 Protein, GLEAN_02449 Protein, FEPS Protein, transient receptor potential cation channel, subfamily A, member 1a Protein, Transient receptor potential cation channel A1 Protein, transient receptor potential cation channel subfamily A member 1 Protein, transient receptor potential A1 Protein, tryptophan synthase subunit alpha 1 Protein, transient receptor potential cation channel, subfamily A, member 1 Protein, TRPA cation channel homolog Protein, trpa1a Protein, TrpA1 Protein, TRPA1 Protein, LOC658860 Protein, LOC694623 Protein, trpA1 Protein, trpa1 Protein, Trpa1 Protein, trpa-1 Protein

Hintergrund: ANKTM1, FEPS, FEPS1
Description: The structure of the protein is highly related to both the protein ankyrin and transmembrane proteins. This protein is activated by a large variety of structurally unrelated electrophilic and non-electrophilic chemical compounds. Electrophilic ligands activate TRPA1 by interacting with critical N-terminal Cys residues in a covalent manner, whereas mechanisms of non-electrophilic ligands are not well determined. May be a component for the mechanosensitive transduction channel of hair cells in inner ear, thereby participating in the perception of sounds. Probably operated by a phosphatidylinositol second messenger system.

Molekulargewicht: The human full length TRPA1 protein has a MW of 127.5 kDa

UniProt: O75762