GPR75 Protein
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- Target Alle GPR75 Proteine anzeigen
- GPR75 (G Protein-Coupled Receptor 75 (GPR75))
- Protein-Typ
- Synthetic
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Verwendungszweck
- Human GPR75 full length protein-synthetic nanodisc
- Produktmerkmale
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product GPR75 Protein
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- Applikationshinweise
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Kommentare
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Haltbarkeit
- 12 months
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- Target
- GPR75 (G Protein-Coupled Receptor 75 (GPR75))
- Andere Bezeichnung
- GPR75 (GPR75 Produkte)
- Synonyme
- GPR75 Protein, GPRchr2 Protein, WI31133 Protein, G protein-coupled receptor 75 Protein, G protein-coupled receptor 75 S homeolog Protein, GPR75 Protein, gpr75 Protein, Gpr75 Protein, gpr75.S Protein
- Hintergrund
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GPRchr2,
Description: WI31133G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor. - Molekulargewicht
- The human full length GPR75 protein has a MW of 59.4 kDa
- UniProt
- O95800
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