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GLP1R Protein (Fc Tag)

GLP1R Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Produktnummer ABIN7491459
  • Target Alle GLP1R Proteine anzeigen
    GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))
    Protein-Typ
    Recombinant
    Spezies
    • 9
    • 4
    • 1
    Human
    Quelle
    • 5
    • 4
    • 2
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses GLP1R Protein ist gelabelt mit Fc Tag.
    Verwendungszweck
    Recombinant Human GLP1R Protein with C-terminal human Fc tag
    Spezifität
    GLP1R (Arg24-Glu139) hFc (Glu99-Ala330)
    Produktmerkmale
    Extracellular Domain Protein
    Reinheit
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product GLP1R Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Haltbarkeit
    12 months
  • Target
    GLP1R (Glucagon-Like Peptide 1 Receptor (GLP1R))
    Andere Bezeichnung
    GLP1R (GLP1R Produkte)
    Synonyme
    GLP1R Protein, LOC100228311 Protein, GLP-1R Protein, GLP1Rc Protein, Glip Protein, RATGL1RCP Protein, glucagon like peptide 1 receptor Protein, glucagon-like peptide 1 receptor Protein, GLP1R Protein, Glp1r Protein
    Hintergrund
    GLP-1, GLP-1-R, GLP-1R
    Description: This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]
    Molekulargewicht
    predicted molecular mass of 39.7 kDa after removal of the signal peptide. The apparent molecular mass of GLP1R-hFc is 35-70 kDa due to glycosylation.
    UniProt
    P43220
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, cAMP Metabolic Process, Feeding Behaviour
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