GIPR Protein (Fc Tag)

Produktnummer ABIN7491455

Produktdetails

Target: GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses GIPR Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Human GIPR Protein with C-terminal human Fc tag

Spezifität: GIPR (Arg22-Gln138) hFc (Glu99-Ala330)

Produktmerkmale: Extracellular Domain Protein

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))

Andere Bezeichnung: GIPR (GIPR Produkte)

Synonyme: GIPR Protein, PGQTL2 Protein, GIP-R Protein, Gm1081 Protein, Gm160 Protein, Gippr Protein, RATGIPPR Protein, gastric inhibitory polypeptide receptor Protein, glucagon receptor Protein, GIPR Protein, LOC100303705 Protein, Gipr Protein

Hintergrund: PGQTL2
Description: This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. [provided by RefSeq, Oct 2011]

Molekulargewicht: predicted molecular mass of 39.6 kDa after removal of the signal peptide. The apparent molecular mass of GIPR-hFc is 35-55 kDa due to glycosylation.

UniProt: P48546

Pathways: Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling