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ACVR1C/ALK7 Protein (Fc Tag)

ACVR1C Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Produktnummer ABIN7491395
  • Target Alle ACVR1C/ALK7 (ACVR1C) Proteine anzeigen
    ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
    Protein-Typ
    Recombinant
    Spezies
    • 9
    • 2
    • 1
    Human
    Quelle
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses ACVR1C/ALK7 Protein ist gelabelt mit Fc Tag.
    Verwendungszweck
    Recombinant Human ACVR1C Protein with C-terminal human Fc tag
    Spezifität
    ACVR1C (Leu22-Glu113) hFc (Glu99-Ala330)
    Produktmerkmale
    Extracellular Domain Protein
    Reinheit
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product ACVR1C Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Haltbarkeit
    12 months
  • Target
    ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
    Andere Bezeichnung
    ACVR1C (ACVR1C Produkte)
    Synonyme
    ACVRLK7 Protein, ALK7 Protein, Alk-7 Protein, C230097P10 Protein, Alk7 Protein, habrec1 Protein, activin A receptor type 1C Protein, activin A receptor, type IC Protein, ACVR1C Protein, Acvr1c Protein
    Hintergrund
    ACVRLK7, ALK7ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008]
    Molekulargewicht
    predicted molecular mass of 36.0 kDa after removal of the signal peptide. The apparent molecular mass of ACVR1C-hFc is 35-70 kDa due to glycosylation.
    UniProt
    Q8NER5
    Pathways
    Negative Regulation of Hormone Secretion, Positive Regulation of Endopeptidase Activity
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