NPR2 Protein (His tag)

Produktnummer ABIN7491319

Produktdetails

Target: NPR2 (Natriuretic Peptide Receptor B/guanylate Cyclase B (Atrionatriuretic Peptide Receptor B) (NPR2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses NPR2 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human ANPRB Protein with C-terminal 6xHis tag

Spezifität: ANPRB (Arg23-Ile458) 6xHis tag

Produktmerkmale: Extracellular Domain Protein

Reinheit: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: NPR2 (Natriuretic Peptide Receptor B/guanylate Cyclase B (Atrionatriuretic Peptide Receptor B) (NPR2))

Andere Bezeichnung: ANPRB (NPR2 Produkte)

Synonyme: NPR2 Protein, GC-B Protein, GC-B2 Protein, GC-B3 Protein, cn Protein, mNPR-B Protein, pwe Protein, AMDM Protein, ANPRB Protein, ANPb Protein, GUC2B Protein, GUCY2B Protein, NPRB Protein, NPRBi Protein, NPR-B Protein, natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) Protein, natriuretic peptide receptor 2 Protein, NPR2 Protein, Npr2 Protein

Hintergrund: AMDM, ANPb, NPR2, ECDM, GC-B, GCB, GUC2B, GUCY2B, NPRB, NPRBi, SNSK
Description: This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq, Jul 2008]

Molekulargewicht: predicted molecular mass of 49.3 kDa after removal of the signal peptide.

UniProt: P20594