VPS4A Protein (His tag)

Produktnummer ABIN7491269

Produktdetails

Target: VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses VPS4A Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human VPS4 Protein with C-terminal 6xHis tag

Spezifität: VPS4 (Met1-Ser437) 6xHis tag

Produktmerkmale: Extracellular Domain Protein

Reinheit: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))

Andere Bezeichnung: VPS4 (VPS4A Produkte)

Synonyme: vsp4 Protein, SKD1 Protein, SKD1A Protein, SKD2 Protein, VPS4 Protein, VPS4-1 Protein, zgc:153907 Protein, 4930589C15Rik Protein, AI325971 Protein, AW553189 Protein, vacuolar protein sorting 4 homolog A Protein, vacuolar sorting protein 4 Protein, vacuolar protein sorting 4 homolog A L homeolog Protein, vacuolar protein sorting 4a homolog A (S. cerevisiae) Protein, vacuolar protein sorting 4A Protein, VPS4A Protein, TP03_0351 Protein, vps4a Protein, vps4a.L Protein, Vps4a Protein

Hintergrund: CIMDAG, SKD1, SKD1A, SKD2, VPS4A, VPS4-1
Description: The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16, the gene for the other resides on chromosome 18. [provided by RefSeq, Jul 2008]

Molekulargewicht: predicted molecular mass of 49.7 kDa after removal of the signal peptide. The apparent molecular mass of VPS4-His is 55-70 kDa due to glycosylation.

UniProt: Q9UN37

Pathways: Microtubule Dynamics, CXCR4-mediated Signaling Events