CXCL7 Protein (His tag)

Produktnummer ABIN7455646

Produktdetails

Target: CXCL7 (PPBP) (Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CXCL7 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human C-X-C Motif Chemokine 7 is produced by our Mammalian expression system and the target gene encoding Ser35-Asp128 is expressed with a 6His tag at the C-terminus.

Produktmerkmale: Extracellular Domain Protein

Reinheit: Greater than 95 % as determined by reducing SDS-PAGE.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: a 0.2 μm filtered solution of 20 mM HAc-Nac, 150 mM NaCl, pH 4.0.

Lagerung: -20 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: CXCL7 (PPBP) (Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP))

Andere Bezeichnung: CXCL7 (PPBP Produkte)

Synonyme: 2400003M24Rik Protein, AI854500 Protein, CTAP3 Protein, CTAPIII Protein, Cxcl7 Protein, LA-PF4 Protein, LDGF Protein, MDGF Protein, NAP-2 Protein, NAP-2-L1 Protein, Scyb7 Protein, TGB Protein, TGB1 Protein, THBGB1 Protein, b-TG1 Protein, beta-TG Protein, B-TG1 Protein, Beta-TG Protein, CTAP-III Protein, CXCL7 Protein, PBP Protein, SCYB7 Protein, TC1 Protein, TC2 Protein, THBGB Protein, Nap-2 Protein, CTAPIII/NAP-2 Protein, Platelet basic protein Protein, pro-platelet basic protein Protein, scyb7 Protein, Ppbp Protein, PPBP Protein

Hintergrund: Platelet Basic Protein, PBP, C-X-C Motif Chemokine 7, Leukocyte-Derived Growth Factor, LDGF, Macrophage-Derived Growth Factor, MDGFSmall-Inducible Cytokine B7, PPBP, CTAP3, CXCL7, SCYB7, TGB1, THBGB1Human Chemokine (C-X-C motif) Ligand 7 (CXCL7), also known as neutrophil activating peptide 2 (NAP-2), is a member of the CXC chemokines containing an ELR domain (Glu-Leu-Arg tripeptide motif). Similar to other ELR domain containing CXC chemokines, such as IL-8 and the GRO proteins, CXCL7 binds CXCR2, chemoattracts and activates neutrophils. CXCL7, Connective Tissue Activating Protein III (CTAPIII) and βthrombogulin (βTG), are proteolytically processed carboxylterminal fragments of platelet basic protein (PBP) which is found in the alphagranules of human platelets. Although CTAPIII, βTG, and PBP represent amino-terminal extended variants of NAP2 and possess the same CXC chemokine domains, these proteins do not exhibit CXCL7/NAP2 activity. CXCL7 induces cell migration through the G-protein-linked receptor CXCR-2.

Molekulargewicht: 11.3 KDa

UniProt: P02775