NG2 Protein (AA 1581-2222) (His tag)

Produktnummer ABIN7454185

Produktdetails

Target: NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1581-2222

Spezies: Cynomolgus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses NG2 Protein ist gelabelt mit His tag.

Verwendungszweck: Cynomolgus CSPG4/MCSP Protein

Sequenz: Ser1581-Ser2222

Produktmerkmale: Recombinant Cynomolgus CSPG4/MCSP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser1581-Ser2222.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))

Andere Bezeichnung: CSPG4 (MCSP Produkte)

Synonyme: HMW-MAA Protein, MCSP Protein, MCSPG Protein, MEL-CSPG Protein, MSK16 Protein, NG2 Protein, 4732461B14Rik Protein, AN2 Protein, Ng2 Protein, HSMCSGEN1 Protein, MCS Protein, chondroitin sulfate proteoglycan 4 Protein, sperm mitochondria associated cysteine rich protein Protein, CSPG4 Protein, Cspg4 Protein, SMCP Protein

Hintergrund: The chondroitin sulfate proteoglycan-4 (CSPG4) is a cell surface proteoglycan overexpressed in a huge range of human and canine neoplastic lesions by tumor cells, tumor microenvironment and cancer initiating cells. CSPG4 plays a central role in the oncogenic pathways required for malignant progression and metastatization.

Molekulargewicht: 69.30 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.

UniProt: A0A2K5UW71

Pathways: Glycosaminoglycan Metabolic Process