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Glucagon Receptor Protein (GCGR) (Biotin,His-Avi Tag)

MALS verified GCGR Spezies: Human Wirt: HEK-293 Cells Recombinant 90,00 %
Produktnummer ABIN7316837
  • Target Alle Glucagon Receptor (GCGR) Proteine anzeigen
    Glucagon Receptor (GCGR)
    Protein-Typ
    Recombinant
    Spezies
    • 6
    • 3
    Human
    Quelle
    • 5
    • 4
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses Glucagon Receptor Protein ist gelabelt mit Biotin,His-Avi Tag.
    Verwendungszweck
    Biotinylated Human GCGR / Glucagon receptor Protein, His,Avitag™ (MALS verified)
    Sequenz
    Ala 26 - Lys 136
    Produktmerkmale
    Biotinylated Human GCGR / Glucagon receptor, His,Avitag is expressed from human 293 cells (HEK293). It contains AA Ala 26 - Lys 136 (Accession # P47871-1).
    Reinheit
    90,00 %
    Endotoxin-Niveau
    1.0 EU per μg
    Güteklasse
    MALS verified
    Top Product
    Discover our top product GCGR Protein
  • Kommentare

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 16.6 kDa. The protein migrates as 27-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C
  • Target
    Glucagon Receptor (GCGR)
    Andere Bezeichnung
    GCGR (GCGR Produkte)
    Synonyme
    GCGR Protein, GGR Protein, GR Protein, glucagon receptor Protein, GCGR Protein, Gcgr Protein
    Hintergrund
    Synonyms:Glucagon R, GCGR,Glucagon receptor,Description:G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
    Molekulargewicht
    16.6 kDa
    Pathways
    Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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