Glucagon Receptor Protein (GCGR) (Biotin,His-Avi Tag)
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- Target Alle Glucagon Receptor (GCGR) Proteine anzeigen
- Glucagon Receptor (GCGR)
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses Glucagon Receptor Protein ist gelabelt mit Biotin,His-Avi Tag.
- Verwendungszweck
- Biotinylated Human GCGR / Glucagon receptor Protein, His,Avitag™ (MALS verified)
- Sequenz
- Ala 26 - Lys 136
- Produktmerkmale
- Biotinylated Human GCGR / Glucagon receptor, His,Avitag is expressed from human 293 cells (HEK293). It contains AA Ala 26 - Lys 136 (Accession # P47871-1).
- Reinheit
- 90,00 %
- Endotoxin-Niveau
- 1.0 EU per μg
- Güteklasse
- MALS verified
- Top Product
- Discover our top product GCGR Protein
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- Kommentare
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This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 16.6 kDa. The protein migrates as 27-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Lagerung
- -20 °C
- Informationen zur Lagerung
- -20°C
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- Target
- Glucagon Receptor (GCGR)
- Andere Bezeichnung
- GCGR (GCGR Produkte)
- Synonyme
- GCGR Protein, GGR Protein, GR Protein, glucagon receptor Protein, GCGR Protein, Gcgr Protein
- Hintergrund
- Synonyms:Glucagon R, GCGR,Glucagon receptor,Description:G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
- Molekulargewicht
- 16.6 kDa
- Pathways
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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