CEACAM6 Protein (Fc Tag)

Produktnummer ABIN7448006

Produktdetails

Target: CEACAM6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CEACAM6 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Human CEACAM-6 / CD66c Protein, Fc Tag (MALS verified)

Sequenz: Lys 35 - Gly 320

Produktmerkmale: Human CEACAM-6, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Lys 35 - Gly 320 (Accession # P40199-1).

Reinheit: 95,00 %

Endotoxin-Niveau: 1.0 EU per μg

Güteklasse: MALS verified

Anwendungsinformationen

Kommentare:

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 57.7 kDa. The protein migrates as 75-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Antigendetails

Target: CEACAM6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6))

Andere Bezeichnung: CEACAM-6 (CEACAM6 Produkte)

Synonyme: CD66c Protein, CEAL Protein, NCA Protein, carcinoembryonic antigen-related cell adhesion molecule 6 Protein, carcinoembryonic antigen related cell adhesion molecule 6 Protein, Ceacam6 Protein, CEACAM6 Protein

Hintergrund: Synonyms:CEACAM6,CD66c,CEAL,NCA,Description:Carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (CEACAM6) is also known as CD66c (Cluster of Differentiation 66c), CEAL, NCA, and is one of seven human CEACAM family members within the immunoglobulin superfamily. In humans, CEACAMs include type I transmembrane proteins (CEACAM1, CEACAM3, and CEACAM4) and GPI-linked molecules (CEACAM5 through CEACAM8). There is no human CEACAM2. CEACAM 6 contains one N-terminal V-type Ig-like domain (N domain), followed by two C2-type Ig-like domains. It shows considerable glycosylation, including (sialyl) LewisX, which mediates binding to E-selectin, galectins and some bacterial fimbrae. CEACAM-6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesion-related apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression.

Molekulargewicht: 57.7 kDa