TGFBR2
(Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))
Protein-Typ
Recombinant
Proteineigenschaft
AA 24-159
Spezies
Human
Quelle
HEK-293 Cells
Aufreinigungstag / Konjugat
Dieses TGFBR2 Protein ist gelabelt mit mFc-Avi Tag.
Verwendungszweck
Human TGF-beta RII/TGFBR2 Protein
Sequenz
Ile24-Asp159
Produktmerkmale
Recombinant Human TGF-beta RII/TGFBR2 Protein is expressed from HEK293 with mFc (IgG1) tag and Avi tag at C-Terminus.It contains Ile24-Asp159.
Reinheit
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Sterilität
0.22 μm filtered
Endotoxin-Niveau
Less than 1EU per μg by the LAL method.
Biological Activity Comment
Immobilized Human Mature TGF beta 1, No Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Human TGF-beta RII, mFc Tag with the EC50 of 8ng/ml determined by ELISA. See testing image for detail.
TGFBR2
Spezies: Ratte
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by SDS-PAGE
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
Buffer
Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
Lagerung
-20 °C,-80 °C
Informationen zur Lagerung
-20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Haltbarkeit
12 months
Target
TGFBR2
(Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called signal transduction. Through this type of signaling, the environment outside the cell affects activities inside the cell such as stimulation of cell growth and division.
Molekulargewicht
44 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result.