SIGLEC8 Protein (AA 17-363) (Fc Tag)
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- Target Alle SIGLEC8 Proteine anzeigen
- SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 17-363
- Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses SIGLEC8 Protein ist gelabelt mit Fc Tag.
- Verwendungszweck
- Human Siglec-8 Protein
- Sequenz
- Met17-Ala363
- Produktmerkmale
- Recombinant Human Siglec-8 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Met17-Ala363.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
- Andere Bezeichnung
- Siglec-8 (SIGLEC8 Produkte)
- Synonyme
- SAF2 Protein, SIGLEC-8 Protein, SIGLEC8L Protein, SIGLEC8 Protein, sialic acid binding Ig like lectin 8 Protein, sialic acid-binding Ig-like lectin 8 Protein, SIGLEC8 Protein, LOC506364 Protein
- Hintergrund
- Siglec-8, also known as SAF, is an approximately 75 kDa transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-8 consists of a 347 amino acid (aa) extracellular domain (ECD) with three Ig-like domains.Putative adhesion molecule that mediates sialic-acid dependent binding to red blood cells. Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid.
- Molekulargewicht
- 64.6 kDa. Due to glycosylation, the protein migrates to 70-82 kDa based on Tris-Bis PAGE result.
- UniProt
- Q9NYZ4
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