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Microseminoprotein, Prostate Associated (MSMP) (AA 37-139) protein (Fc Tag)

MSMP Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7275492
  • Target Alle Microseminoprotein, Prostate Associated (MSMP) Proteine anzeigen
    Microseminoprotein, Prostate Associated (MSMP)
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 37-139
    Spezies
    • 2
    • 2
    Human
    Quelle
    • 2
    • 2
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Fc Tag
    Verwendungszweck
    Human PSMP Protein
    Sequenz
    Lys37-Ser139
    Produktmerkmale
    Recombinant Human PSMP Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Lys37-Ser139.
    Reinheit
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product MSMP Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Microseminoprotein, Prostate Associated (MSMP)
    Andere Bezeichnung
    PSMP (MSMP Produkte)
    Synonyme
    PSMP Protein, OTTMUSG00000007017 Protein, Psmp Protein, microseminoprotein, prostate associated Protein, MSMP Protein, Msmp Protein
    Hintergrund
    PC3-secreted microprotein (PSMP)/microseminoprotein (MSMP) is a novel chemotactic cytokine and its receptor is CCR2. PSMP was highly expressed in fibrotic/cirrhotic tissues from patients with different etiologies of liver disease and in the 3 experimental mouse models of fibrosis. Damage-associated molecular pattern molecules HMGB-1 and IL-33 induced hepatocytes to produce PSMP. PSMP promotes liver fibrosis through inflammatory macrophage infiltration, polarization and production of proinflammatory cytokines, as well as direct activation of hepatic stellate cells via its receptor CCR2.
    Molekulargewicht
    37.9 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Tris-Bis PAGE result.
    UniProt
    Q1L6U9
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