WFDC1 Protein (AA 24-211) (His tag)
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- Target Alle WFDC1 Proteine anzeigen
- WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 24-211
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Spezies
- Maus
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses WFDC1 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Mouse PS20 Protein
- Sequenz
- Gln24-Pro211
- Produktmerkmale
- Recombinant Mouse PS20 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Gln24-Pro211.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))
- Andere Bezeichnung
- PS20 (WFDC1 Produkte)
- Synonyme
- WFDC1 Protein, zgc:158671 Protein, PS20 Protein, 2310058A03Rik Protein, ps20 Protein, WAP four-disulfide core domain 1 Protein, WFDC1 Protein, wfdc1 Protein, Wfdc1 Protein
- Hintergrund
- The whey acidic protein family member, WFDC1/ps20 is a permissivity factor in HIV infection. Herein we describe a contrasting role for ps20 in limiting MHV-1 infection. Intranasal MHV-1 infection produces a respiratory infection in mice. Using ps20 knockout mice we provide evidence that intranasal MHV-1 infection results in increased lung viral titers in ps20(-/-) compared to ps20(/) mice. Roles for ps20 in regulating expression of neutrophil-specific chemotactic factors, thereby potentially modulating neutrophil migration, and in modulating neutrophil susceptibility to MHV-1 infection.
- Molekulargewicht
- 21.9 kDa. The protein migrates to 27-30 kDa based on Tris-Bis PAGE result.
- UniProt
- Q9ESH5
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