PILRA Protein (AA 32-197) (His tag)

Produktnummer ABIN7275475

Produktdetails

Target: PILRA (Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA))

Protein-Typ: Recombinant

Proteineigenschaft: AA 32-197

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PILRA Protein ist gelabelt mit His tag.

Verwendungszweck: Mouse PILRA Protein

Sequenz: Glu32-Val197

Produktmerkmale: Recombinant Mouse PILRA Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu32-Val197.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: PILRA (Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA))

Andere Bezeichnung: PILRA (PILRA Produkte)

Synonyme: PILRA Protein, FDF03 Protein, AV021745 Protein, RGD1562847 Protein, paired immunoglobin like type 2 receptor alpha Protein, paired immunoglobulin-like type 2 receptor alpha Protein, paired immunoglobin-like type 2 receptor alpha Protein, PILRA Protein, LOC489841 Protein, Pilra Protein

Hintergrund: Alzheimer's disease (AD) is a neurodegenerative disease characterized by a progressive decline in cognitive performance, Mild Cognitive Impairment (MCI) is instead an objective decline in cognitive performance that does not reach pathology. Paired immunoglobulin-like type 2 receptor alpha (PILRA) is a cell surface inhibitory receptor that was recently suggested to be involved in AD pathogenesis. In particular, the arginine-to-glycine substitution in position 78 (R78, rs1859788) was shown to be protective against AD.

Molekulargewicht: 19.71 kDa. Due to glycosylation, the protein migrates to 43-60 kDa based on Tris-Bis PAGE result.