Phospholipase D4 Protein (PLD4) (AA 52-506) (His tag)

Produktnummer ABIN7275464

Produktdetails

Target: Phospholipase D4 (PLD4)

Protein-Typ: Recombinant

Proteineigenschaft: AA 52-506

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Phospholipase D4 Protein ist gelabelt mit His tag.

Verwendungszweck: Human PLD4 Protein

Sequenz: Trp52-Gly506

Produktmerkmale: Recombinant Human PLD4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Trp52-Gly506.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in 50 mM MES, 100 mM NaCl ( pH 6.0).

Buffer: Lyophilized from 0.22μm filtered solution in 50 mM MES, 100 mM NaCl ( pH 6.0). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Phospholipase D4 (PLD4)

Andere Bezeichnung: PLD4 (PLD4 Produkte)

Synonyme: C14orf175 Protein, AI132321 Protein, thss Protein, phospholipase D family member 4 Protein, phospholipase D family, member 4 Protein, PLD4 Protein, Pld4 Protein

Hintergrund: Phospholipase D4 (PLD4) is a newly identified protein expressed in microglia. the expression of PLD4 was located in macrophages in the colon cancer mesenchymal and lymph nodes as shown by immunohistochemical analysis. furthermore, its expression was associated with clinical staging of colon cancer. Then, THP-1 as a cell model induced into TAMs. PLD4 could be involved in the activation process of M1 phenotype macrophages.

Molekulargewicht: 51.1 kDa. Due to glycosylation, the protein migrates to 68-75 kDa based on Tris-Bis PAGE result.

UniProt: Q96BZ4