NCR1 Protein (AA 22-254) (His tag,Biotin)

Produktnummer ABIN7275349

Produktdetails

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 22-254

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses NCR1 Protein ist gelabelt mit His tag,Biotin.

Verwendungszweck: Biotinylated Human NKp46/NCR1/CD335 Protein (Primary Amine Labeling)

Sequenz: Gln22-Asn254

Produktmerkmale: Recombinant Biotinylated Human NKp46/NCR1/CD335 Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the N-Terminus.It contains Gln22-Asn254.

Reinheit: > 95 % as determined by Tris-Bis PAGE

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Anti-Nkp46 Antibody, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human NKp46, His Tag with the EC50 of 3.1ng/ml determined by ELISA. See testing image for detail.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in PBS ( pH 7.4).

Lagerung: -80 °C

Informationen zur Lagerung: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Andere Bezeichnung: NKp46 (NCR1 Produkte)

Synonyme: CD335 Protein, LY94 Protein, NK-p46 Protein, NKP46 Protein, Ly94 Protein, NKp46 Protein, KILR-1 Protein, Nk-p46 Protein, Nkp46 Protein, natural cytotoxicity triggering receptor 1 Protein, NCR1 Protein, Ncr1 Protein

Hintergrund: NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells.

Molekulargewicht: 27.5 kDa. Due to glycosylation, the protein migrates to 38-48 kDa based on Tris-Bis PAGE result.

Pathways: Regulation of Leukocyte Mediated Immunity