KLRC2 Protein (AA 94-231) (His tag)

Produktnummer ABIN7275333

Produktdetails

Target: KLRC2 (Killer Cell Lectin-Like Receptor Subfamily C, Member 2 (KLRC2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 94-231

Spezies: Cynomolgus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses KLRC2 Protein ist gelabelt mit His tag.

Verwendungszweck: Cynomolgus NKG2C/CD159c Protein

Sequenz: Ile94-Leu231

Produktmerkmale: Recombinant Cynomolgus NKG2C/CD159c Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Ile94-Leu231.

Reinheit: > 95 % as determined by Tris-Bis PAGE

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: KLRC2 (Killer Cell Lectin-Like Receptor Subfamily C, Member 2 (KLRC2))

Andere Bezeichnung: NKG2C (KLRC2 Produkte)

Synonyme: CD159c Protein, NKG2-C Protein, NKG2C Protein, killer cell lectin like receptor C2 Protein, killer cell lectin-like receptor subfamily C, member 2 Protein, KLRC2 Protein

Hintergrund: As a first line of defense, natural killer (NK) cells play a crucial role in the fight against infections. The presented study is the first of its kind that ascribes CD56dimCD16 NKG2C-expressing NK cells a crucial role in biasing adaptive immune responses upon influenza vaccination and suggests NKG2C as a potential biomarker in predicting pandemic influenza vaccine responsiveness.

Molekulargewicht: 16.9 kDa. Due to glycosylation, the protein migrates to 25-30 kDa based on Tris-Bis PAGE result.