Lipocalin 2 Protein (LCN2) (AA 21-200) (Fc Tag)

Produktnummer ABIN7275322

Produktdetails

Target: Lipocalin 2 (LCN2)

Protein-Typ: Recombinant

Proteineigenschaft: AA 21-200

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Lipocalin 2 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Mouse NGAL/Lipocalin-2 Protein

Sequenz: Gln21-Asn200

Produktmerkmale: Recombinant Mouse NGAL/Lipocalin-2 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln21-Asn200.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in 50 mM MES,150 mM NaCl ( pH 6.5).

Buffer: Lyophilized from 0.22μm filtered solution in 50 mM MES,150 mM NaCl ( pH 6.5). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Lipocalin 2 (LCN2)

Andere Bezeichnung: NGAL (LCN2 Produkte)

Synonyme: LCN2 Protein, 24p3 Protein, MSFI Protein, NGAL Protein, AW212229 Protein, Sip24 Protein, lipocalin 2 Protein, LCN2 Protein, Lcn2 Protein

Hintergrund: Acute kidney injury (AKI) is one of the most common complications of various serious conditions, and early diagnosis is therefore critical for the treatment of AKI. Recent evidence demonstrates that neutrophil gelatinase- associated lipocalin (NGAL) is closely associated with AKI. Several experimental and clinical studies have shown that the expression of urine and serum NGAL increases significantly in AKI. NGAL shows potential to be a new effective early biochemical marker of AKI. Further studies are needed to confirm the significant advantages of NGAL in the diagnosis of early AKI and its value in clinical applications.

Molekulargewicht: 47.5 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.

UniProt: P11672

Pathways: Cellular Response to Molecule of Bacterial Origin, Transition Metal Ion Homeostasis