LYPD3 Protein (AA 31-286) (His tag)

Produktnummer ABIN7275199

Produktdetails

Target: LYPD3 (LY6/PLAUR Domain Containing 3 (LYPD3))

Protein-Typ: Recombinant

Proteineigenschaft: AA 31-286

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses LYPD3 Protein ist gelabelt mit His tag.

Verwendungszweck: Human LYPD3 Protein

Sequenz: Leu31-His286

Produktmerkmale: Recombinant Human LYPD3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu31-His286.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human LYPD3, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-LYPD3 Ab., hFc Tag with the EC50 of 11.6ng/ml determined by ELISA. See testing image for detail.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: LYPD3 (LY6/PLAUR Domain Containing 3 (LYPD3))

Andere Bezeichnung: LYPD3 (LYPD3 Produkte)

Synonyme: LYPD3 Protein, MGC139913 Protein, C4.4A Protein, 2310061G07Rik Protein, C4.4a Protein, LY6/PLAUR domain containing 3 Protein, Ly6/Plaur domain containing 3 Protein, LYPD3 Protein, Lypd3 Protein

Hintergrund: Aberrant expression of LYPD3 plays an oncogenic role in several types of cancer. LYPD3 was highly expressed in LUAD tumor compared with paracancerous tissues.Furthermore, the expression of LYPD3 was able to be regulated by the methylation in LYPD3 promoter region, which was positively associated with the overall survival. LYPD3 might affect the clinical manifestations of LUAD by regulating the P53 signaling pathway.

Molekulargewicht: 27.8 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.

UniProt: O95274