LILRB5 Protein (AA 18-456) (His-Avi Tag)

Produktnummer ABIN7275193

Produktdetails

Target: LILRB5 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 5 (LILRB5))

Protein-Typ: Recombinant

Proteineigenschaft: AA 18-456

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses LILRB5 Protein ist gelabelt mit His-Avi Tag.

Verwendungszweck: Human LILRB5/CD85c/LIR-8 Protein

Sequenz: Arg18-His456

Produktmerkmale: Recombinant Human LILRB5/CD85c/LIR-8 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Arg18-His456.

Reinheit: > 95 % as determined by Tris-Bis PAGE

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: LILRB5 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 5 (LILRB5))

Andere Bezeichnung: LILRB5 (LILRB5 Produkte)

Synonyme: LILRB5 Protein, CD85C Protein, LIR-8 Protein, LIR8 Protein, leukocyte immunoglobulin-like receptor subfamily B member 5 Protein, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 Protein, leukocyte immunoglobulin like receptor B5 Protein, LOC695256 Protein, LILRB5 Protein

Hintergrund: LILRB5, also known as CD85c andLIR-8, belongs to a family of transmembrane glycoproteins that negatively regulate immune cell activation. Mature human LIR-8 consists of a 435 amino acid (aa) extracellular domain with four Ig-like domains, a 21 aa transmembrane segment, and a 111 aa cytoplasmic domain with two immunoreceptor tyrosine-based inhibitory motifs (ITIM). LILRB5 may act as receptor for class I MHC antigens.

Molekulargewicht: 49.9 kDa. Due to glycosylation, the protein migrates to 67-72 kDa based on Tris-Bis PAGE result.