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KLRG1 Protein (AA 57-188) (Fc Tag)

KLRG1 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7275100
  • Target Alle KLRG1 Proteine anzeigen
    KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 57-188
    Spezies
    • 10
    • 3
    Maus
    Quelle
    • 4
    • 3
    • 2
    • 2
    • 2
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses KLRG1 Protein ist gelabelt mit Fc Tag.
    Verwendungszweck
    Mouse KLRG1 Protein
    Sequenz
    Gln57-Tyr188
    Produktmerkmale
    Recombinant Mouse KLRG1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Gln57-Tyr188.
    Reinheit
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product KLRG1 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))
    Andere Bezeichnung
    KLRG1 (KLRG1 Produkte)
    Synonyme
    KLRG1 Protein, 2F1-Ag Protein, MAFA Protein, MAFA-L Protein, 2F1 Protein, CLEC15A Protein, MAFA-2F1 Protein, MAFA-LIKE Protein, killer cell lectin like receptor G1 Protein, killer cell lectin-like receptor subfamily G, member 1 Protein, KLRG1 Protein, Klrg1 Protein
    Hintergrund
    Immune homeostasis requires the tight, tissue-specific control of the different CD4 Foxp3 regulatory T (Treg) cell populations. The cadherin-binding inhibitory receptor killer cell lectin-like receptor G1 (KLRG1) is expressed by a subpopulation of Treg cells with GATA3 effector phenotype.Lack of KLRG1 on Treg cells conferred on them a competitive advantage in the gut, but not in lymphoid organs. Hence, although absence of KLRG1 is not enough to increase intestinal Treg cells in KLRG1 knockout mice, KLRG1 ligation reduces T-cell receptor signals and the competitive fitness of individual Treg cells in the intestine.
    Molekulargewicht
    42.3 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Tris-Bis PAGE result.
    UniProt
    O88713
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