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Klotho beta Protein (KLB) (AA 53-994) (His tag)

KLB Spezies: Maus Wirt: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
Produktnummer ABIN7275093
  • Target Alle Klotho beta (KLB) Proteine anzeigen
    Klotho beta (KLB)
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 53-994
    Spezies
    • 5
    • 4
    • 1
    • 1
    Maus
    Quelle
    • 4
    • 3
    • 2
    • 2
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses Klotho beta Protein ist gelabelt mit His tag.
    Verwendungszweck
    Mouse Beta Klotho Protein
    Sequenz
    Phe53-Pro994
    Produktmerkmale
    Recombinant Mouse Beta Klotho Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe53-Pro994.
    Reinheit
    > 90 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product KLB Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Klotho beta (KLB)
    Andere Bezeichnung
    Beta Klotho (KLB Produkte)
    Synonyme
    KLB Protein, BKL Protein, AV071179 Protein, betaKlotho Protein, Klb-ps1 Protein, RGD1308227 Protein, klotho beta Protein, KLB Protein, Klb Protein
    Hintergrund
    Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites.
    Molekulargewicht
    109.91 kDa. Due to glycosylation, the protein migrates to 120-130 kDa based on Tris-Bis PAGE result.
    Pathways
    Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Growth Factor Binding
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