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IL20RA Protein (AA 33-253) (Fc Tag)

IL20RA Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Produktnummer ABIN7274931
  • Target Alle IL20RA Proteine anzeigen
    IL20RA (Interleukin 20 Receptor alpha (IL20RA))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 33-253
    Spezies
    • 8
    • 4
    • 1
    Maus
    Quelle
    • 5
    • 4
    • 2
    • 2
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses IL20RA Protein ist gelabelt mit Fc Tag.
    Verwendungszweck
    Mouse IL-20RA Protein
    Sequenz
    Val33-Lys253
    Produktmerkmale
    Recombinant Mouse IL-20RA Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Val33-Lys253.
    Reinheit
    > 95 % as determined by Tris-Bis PAGE
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    The affinity constant of 14.26 μM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    IL20RA (Interleukin 20 Receptor alpha (IL20RA))
    Andere Bezeichnung
    IL-20RA (IL20RA Produkte)
    Synonyme
    CRF2-8 Protein, IL-20R-alpha Protein, IL-20R1 Protein, IL-20RA Protein, E230031K19 Protein, interleukin 20 receptor subunit alpha Protein, interleukin 20 receptor, alpha Protein, IL20RA Protein, Il20ra Protein
    Hintergrund
    IL-20RA was highly expressed in the tumor tissue of CRC and related to the advanced stage.IL-20RA was involved in regulating oncogenic and immune pathways and affecting the expression of genes related to cell proliferation and immune evasion in CRC.Super-enhancer inhibition by JQ-1 or iBET-151 suppressed the growth of tumor cells and inhibited the expression of IL-20RA.
    Molekulargewicht
    52.1 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Tris-Bis PAGE result.
    UniProt
    Q6PHB0
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