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Hemopexin Protein (HPX) (AA 24-460) (His tag)

HPX Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7274828
  • Target Alle Hemopexin (HPX) Proteine anzeigen
    Hemopexin (HPX)
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 24-460
    Spezies
    • 10
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Quelle
    • 8
    • 6
    • 5
    • 2
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses Hemopexin Protein ist gelabelt mit His tag.
    Verwendungszweck
    Mouse HPX Protein
    Sequenz
    Ser24-Gln460
    Produktmerkmale
    Recombinant Mouse HPX Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser24-Gln460.
    Reinheit
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in 50 mM MES, 150 mM NaCl ( pH 6.0).
    Buffer
    Lyophilized from 0.22μm filtered solution in 50 mM MES, 150 mM NaCl ( pH 6.0). Normally 8 % trehalose is added as protectant before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Hemopexin (HPX)
    Andere Bezeichnung
    HPX (HPX Produkte)
    Synonyme
    HPX Protein, HX Protein, Hpxn Protein, hx Protein, wu:fi17f11 Protein, wu:fi19a10 Protein, hemopexin Protein, HPX Protein, Mmar10_1124 Protein, Hpx Protein, hpx Protein
    Hintergrund
    Hemopexin (HPX) serves as scavenger and transporter of toxic plasma heme to the liver. HPX is formed by two four-bladed beta-propeller domains, resembling two thick disks that lock together at a 90 degrees angle. The heme is bound between the two beta-propeller domains in a pocket formed by the interdomain linker peptide.HPX, acting not only as a heme carrier but also displaying transient heme-based ligand binding and (pseudo-)enzymatic properties, could be considered a 'chronosteric' heme-protein.
    Molekulargewicht
    50 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Tris-Bis PAGE result.
    UniProt
    Q91X72
    Pathways
    Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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