Hepsin Protein (HPN) (AA 45-417) (His tag)

Produktnummer ABIN7274824

Produktdetails

Target: Hepsin (HPN)

Protein-Typ: Recombinant

Proteineigenschaft: AA 45-417

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Hepsin Protein ist gelabelt mit His tag.

Verwendungszweck: Human HPN Protein

Sequenz: Arg45-Leu417

Produktmerkmale: Recombinant Human HPN Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Arg45-Leu417.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human HPN, His Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Anti-HPN Antibody, hFc Tag with the EC50 of 22.8ng/ml determined by ELISA. See testing image for detail.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in 20 mM NaAc,150 mM NaCl ( pH 5.0).

Buffer: Lyophilized from 0.22μm filtered solution in 20 mM NaAc,150 mM NaCl ( pH 5.0). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Hepsin (HPN)

Andere Bezeichnung: HPN (HPN Produkte)

Synonyme: TMPRSS1 Protein, Hlb320 Protein, hepsin Protein, si:dkey-33i11.3 Protein, HPN Protein, si:dkey-33i11.3 Protein, Hpn Protein

Hintergrund: Home parenteral nutrition (HPN) has been proposed as the treatment of choice in patients suffering from intestinal failure (IF) and has been claimed to improve survival and quality of life either in patients with benign disorders or even in those with malignancies. HPN seems to have beneficial effect but it should be considered with caution by the physicians who should take into account the indications of each patient to receive parenteral nutrition, the underlying disease and prognosis and the access of each patient to home care services.

Molekulargewicht: 42 kDa. Due to the protein cleaved into the following two chains, so it migrates to 18-22 kDa and 30 kDa based on Tris-Bis PAGE result.

UniProt: P05981

Pathways: Regulation of Hormone Metabolic Process, Sensory Perception of Sound