GP6 Protein (AA 22-265) (His tag)

Produktnummer ABIN7274761

Produktdetails

Target: GP6 (Glycoprotein VI (Platelet) (GP6))

Protein-Typ: Recombinant

Proteineigenschaft: AA 22-265

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses GP6 Protein ist gelabelt mit His tag.

Verwendungszweck: Mouse GPVI Protein

Sequenz: Gln22-Lys265

Produktmerkmale: Recombinant Mouse GPVI Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln22-Lys265.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: GP6 (Glycoprotein VI (Platelet) (GP6))

Andere Bezeichnung: GPVI (GP6 Produkte)

Synonyme: BDPLT11 Protein, GPIV Protein, GPVI Protein, 9830166G18Rik Protein, Gm469 Protein, Gpvi Protein, GP6 Protein, glycoprotein VI platelet Protein, glycoprotein 6 (platelet) Protein, glycoprotein VI Protein, platelet glycoprotein VI Protein, GP6 Protein, Gp6 Protein, LOC103346235 Protein

Hintergrund: Although platelets are best known for their role in hemostasis, they are also crucial in development, host defense, inflammation, and tissue repair. Many of these roles are regulated by the immune-like receptors glycoprotein VI (GPVI) and C-type lectin receptor 2 (CLEC-2), which signal through an immunoreceptor tyrosine-based activation motif (ITAM). GPVI is activated by collagen in the subendothelial matrix, by fibrin and fibrinogen in the thrombus, and by a remarkable number of other ligands.

Molekulargewicht: 28 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.

UniProt: P0C191