Folate Receptor 4 Protein (AA 20-228) (His tag)

Produktnummer ABIN7274665

Produktdetails

Target: Folate Receptor 4 (FOLR4) (Folate Receptor 4 (Delta) (FOLR4))

Protein-Typ: Recombinant

Proteineigenschaft: AA 20-228

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Folate Receptor 4 Protein ist gelabelt mit His tag.

Verwendungszweck: Human FOLR4/Juno Protein

Sequenz: Gly20-Ser228

Produktmerkmale: Recombinant Human FOLR4/Juno Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly20-Ser228.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Folate Receptor 4 (FOLR4) (Folate Receptor 4 (Delta) (FOLR4))

Andere Bezeichnung: FOLR4 (FOLR4 Produkte)

Synonyme: 0910001L11Rik Protein, C86255 Protein, Folbp3 Protein, IZUMO1 receptor, JUNO Protein, Izumo1r Protein, IZUMO1R Protein

Hintergrund: Izumo1 is the only essential sperm-egg fusion protein currently known on mammalian sperm, and its egg receptor (Juno, formerly Folr4) was recently discovered. Male knockout mice for Izumo1 and female knockout mice for Juno are both healthy but sterile. Here, both sperm-egg binding proteins are shown to be evolving under positive selection. Juno's presence in mammals alone, suggesting a recent mammalian-specific duplication and neofunctionalization of the ancestral folate receptor.

Molekulargewicht: 25 kDa. Due to glycosylation, the protein migrates to 30-35 kDa based on Tris-Bis PAGE result.