DLL3 Protein (AA 27-490) (His tag)

Produktnummer ABIN7274489

Produktdetails

Target: DLL3 (delta Like Protein 3 (DLL3))

Protein-Typ: Recombinant

Proteineigenschaft: AA 27-490

Spezies: Rhesusaffen

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses DLL3 Protein ist gelabelt mit His tag.

Verwendungszweck: Rhesus macaque DLL3 Protein

Sequenz: Ala27-Arg490

Produktmerkmale: Recombinant Rhesus macaque DLL3 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Ala27-Arg490.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Rhesus macaque DLL3, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-DLL3 Antibody, hFc Tag with the EC50 of 2.7ng/ml determined by ELISA. See testing image for detail.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in 20 mM Tris, 50 mM NaCl, 200 mM L-arginine ( pH 8.5). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: DLL3 (delta Like Protein 3 (DLL3))

Andere Bezeichnung: DLL3 (DLL3 Produkte)

Synonyme: SCDO1 Protein, pu Protein, pudgy Protein, delta like canonical Notch ligand 3 Protein, delta-like 3 (Drosophila) Protein, DLL3 Protein, Dll3 Protein

Hintergrund: Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity).

Molekulargewicht: 51 kDa. Due to glycosylation,the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.

UniProt: F6TFV4

Pathways: Notch Signalweg