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CXCL13 Protein (AA 23-109) (Fc Tag)

CXCL13 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Produktnummer ABIN7274443
  • Target Alle CXCL13 Proteine anzeigen
    CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 23-109
    Spezies
    • 11
    • 7
    • 3
    • 1
    • 1
    Human
    Quelle
    • 17
    • 2
    • 2
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses CXCL13 Protein ist gelabelt mit Fc Tag.
    Verwendungszweck
    Human CXCL13/BCA-1 Protein
    Sequenz
    Val23-Per109
    Produktmerkmale
    Recombinant Human CXCL13/BCA-1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Val23-Per109.
    Reinheit
    > 95 % as determined by Tris-Bis PAGE
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human CXCL13, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Anti-CXCL13 Antibody, hFc Tag with the EC50 of 17.2ng/ml determined by ELISA. See testing image for detail.
    Top Product
    Discover our top product CXCL13 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Supplied as 0.22μm filtered solution in 50 mM Tris,500 mM NaCl ( pH 7.4).
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))
    Andere Bezeichnung
    CXCL13 (CXCL13 Produkte)
    Synonyme
    4631412M08Rik Protein, ANGIE2 Protein, Angie Protein, BCA-1 Protein, BLC Protein, BLR1L Protein, Scyb13 Protein, ANGIE Protein, BCA1 Protein, SCYB13 Protein, C-X-C motif chemokine ligand 13 Protein, chemokine (C-X-C motif) ligand 13 Protein, Cxcl13 Protein, CXCL13 Protein
    Hintergrund
    Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice.
    Molekulargewicht
    37.6 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
    UniProt
    O43927
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